Need help (LEFT CLICK NOT WORKING PROPER?)

I can't play anymore. I can't use my left mouse click for what I used to use it for. I can't click on champions/monsters/turrets. I can't move with left mouse click anymore now its with right? I can't cast my spells with left anymore.. But if I go in shop (What I have to open with right mouse to) I can buy items with LEFT. Can someone please explain me or help me? I looked a little bit on the internet and I see people to change config settings I tried to do that but its not working and to be fair I don't understand things like that.. Can someone please help me out..
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