Are item macros allowed?

So I got a mouse that allows me to set macros and I had a question. Can I set, let's say for example, {{item:3146}}Hextech Gunblade or {{item:3340}}Wards to automatically be used at a press of a button?
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We're testing a new feature that gives the option to view discussion comments in chronological order. Some testers have pointed out situations in which they feel a linear view could be helpful, so we'd like see how you guys make use of it.

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