Unknown error

I have the last few days gotten this "Unknown error. An unknown error has occured" etc and it goes ot to say to visit the forums if it remains, and it has. What that does is among others that I can not enter the mastery page while in champion selection, cause that page moved anount 2 cm to the right and ther accept and the X button is outside the client and can not be seen so if I open the mastery/skills page then i can not close it I tried repairing and it does nothing, I tried flushing dns, nothing....
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