players with disabilities

My friend suffers from a disability and he sometimes watches me play league, he absolutely loves the game and has tried playing it, he is okay v bots, as he has time to think and react .. but in pvp he struggles alot..he cant pull of combos as smooth as he could if he was able bodied. I understand changing the game to suit those with disabilities is a big ask, but do you think there could be anything done to help disabled players to be as good as those who are not disabled?
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